diff --git a/changelog.txt b/changelog.txt
index 07ad1612..fdb9d37c 100644
--- a/changelog.txt
+++ b/changelog.txt
@@ -7,6 +7,7 @@ OPENSEADRAGON CHANGELOG
 * DEPRECATION: The OpenSeadragon.createCallback function is no longer recommended (#2367 @akansjain)
 * The viewer now uses WebGL when available (#2310, #2462, #2466, #2468, #2469, #2472, #2478, #2488, #2492, #2521, #2537 @pearcetm, @Aiosa, @thec0keman)
 * Added webp to supported image formats (#2455 @BeebBenjamin)
+* Added avif to supported image formats (#2544 @msalsbery)
 * Introduced maxTilesPerFrame option to allow loading more tiles simultaneously (#2387 @jetic83)
 * Now when creating a viewer or navigator, we leave its position style alone if possible (#2393 @VIRAT9358)
 * Added getter & setter for Viewport.maxZoomPixelRatio (#2506 @eug-L)
diff --git a/package-lock.json b/package-lock.json
index ac650b70..ed1e1e9a 100644
--- a/package-lock.json
+++ b/package-lock.json
@@ -571,6 +571,18 @@
                 "concat-map": "0.0.1"
             }
         },
+        "node_modules/braces": {
+            "version": "3.0.3",
+            "resolved": "https://registry.npmjs.org/braces/-/braces-3.0.3.tgz",
+            "integrity": "sha512-yQbXgO/OSZVD2IsiLlro+7Hf6Q18EJrKSEsdoMzKePKXct3gvD8oLcOQdIzGupr5Fj+EDe8gO/lxc1BzfMpxvA==",
+            "dev": true,
+            "dependencies": {
+                "fill-range": "^7.1.1"
+            },
+            "engines": {
+                "node": ">=8"
+            }
+        },
         "node_modules/browserslist": {
             "version": "4.21.5",
             "resolved": "https://registry.npmjs.org/browserslist/-/browserslist-4.21.5.tgz",
@@ -1740,6 +1752,18 @@
                 "node": "^10.12.0 || >=12.0.0"
             }
         },
+        "node_modules/fill-range": {
+            "version": "7.1.1",
+            "resolved": "https://registry.npmjs.org/fill-range/-/fill-range-7.1.1.tgz",
+            "integrity": "sha512-YsGpe3WHLK8ZYi4tWDg2Jy3ebRz2rXowDxnld4bkQB00cc/1Zw9AWnC0i9ztDJitivtQvaI9KaLyKrc+hBW0yg==",
+            "dev": true,
+            "dependencies": {
+                "to-regex-range": "^5.0.1"
+            },
+            "engines": {
+                "node": ">=8"
+            }
+        },
         "node_modules/finalhandler": {
             "version": "1.1.2",
             "dev": true,
@@ -1772,39 +1796,6 @@
                 "node": ">= 10.13.0"
             }
         },
-        "node_modules/findup-sync/node_modules/braces": {
-            "version": "3.0.2",
-            "resolved": "https://registry.npmjs.org/braces/-/braces-3.0.2.tgz",
-            "integrity": "sha512-b8um+L1RzM3WDSzvhm6gIz1yfTbBt6YTlcEKAvsmqCZZFw46z626lVj9j1yEPW33H5H+lBQpZMP1k8l+78Ha0A==",
-            "dev": true,
-            "dependencies": {
-                "fill-range": "^7.0.1"
-            },
-            "engines": {
-                "node": ">=8"
-            }
-        },
-        "node_modules/findup-sync/node_modules/fill-range": {
-            "version": "7.0.1",
-            "resolved": "https://registry.npmjs.org/fill-range/-/fill-range-7.0.1.tgz",
-            "integrity": "sha512-qOo9F+dMUmC2Lcb4BbVvnKJxTPjCm+RRpe4gDuGrzkL7mEVl/djYSu2OdQ2Pa302N4oqkSg9ir6jaLWJ2USVpQ==",
-            "dev": true,
-            "dependencies": {
-                "to-regex-range": "^5.0.1"
-            },
-            "engines": {
-                "node": ">=8"
-            }
-        },
-        "node_modules/findup-sync/node_modules/is-number": {
-            "version": "7.0.0",
-            "resolved": "https://registry.npmjs.org/is-number/-/is-number-7.0.0.tgz",
-            "integrity": "sha512-41Cifkg6e8TylSpdtTpeLVMqvSBEVzTttHvERD741+pnZ8ANv0004MRL43QKPDlK9cGvNp6NZWZUBlbGXYxxng==",
-            "dev": true,
-            "engines": {
-                "node": ">=0.12.0"
-            }
-        },
         "node_modules/findup-sync/node_modules/micromatch": {
             "version": "4.0.5",
             "resolved": "https://registry.npmjs.org/micromatch/-/micromatch-4.0.5.tgz",
@@ -1818,18 +1809,6 @@
                 "node": ">=8.6"
             }
         },
-        "node_modules/findup-sync/node_modules/to-regex-range": {
-            "version": "5.0.1",
-            "resolved": "https://registry.npmjs.org/to-regex-range/-/to-regex-range-5.0.1.tgz",
-            "integrity": "sha512-65P7iz6X5yEr1cwcgvQxbbIw7Uk3gOy5dIdtZ4rDveLqhrdJP+Li/Hx6tyK0NEb+2GCyneCMJiGqrADCSNk8sQ==",
-            "dev": true,
-            "dependencies": {
-                "is-number": "^7.0.0"
-            },
-            "engines": {
-                "node": ">=8.0"
-            }
-        },
         "node_modules/fined": {
             "version": "1.2.0",
             "dev": true,
@@ -3102,6 +3081,15 @@
                 "node": ">=0.10.0"
             }
         },
+        "node_modules/is-number": {
+            "version": "7.0.0",
+            "resolved": "https://registry.npmjs.org/is-number/-/is-number-7.0.0.tgz",
+            "integrity": "sha512-41Cifkg6e8TylSpdtTpeLVMqvSBEVzTttHvERD741+pnZ8ANv0004MRL43QKPDlK9cGvNp6NZWZUBlbGXYxxng==",
+            "dev": true,
+            "engines": {
+                "node": ">=0.12.0"
+            }
+        },
         "node_modules/is-number-like": {
             "version": "1.0.8",
             "dev": true,
@@ -3353,28 +3341,6 @@
                 "node": ">=10"
             }
         },
-        "node_modules/liftup/node_modules/braces": {
-            "version": "3.0.2",
-            "dev": true,
-            "license": "MIT",
-            "dependencies": {
-                "fill-range": "^7.0.1"
-            },
-            "engines": {
-                "node": ">=8"
-            }
-        },
-        "node_modules/liftup/node_modules/fill-range": {
-            "version": "7.0.1",
-            "dev": true,
-            "license": "MIT",
-            "dependencies": {
-                "to-regex-range": "^5.0.1"
-            },
-            "engines": {
-                "node": ">=8"
-            }
-        },
         "node_modules/liftup/node_modules/findup-sync": {
             "version": "4.0.0",
             "dev": true,
@@ -3389,14 +3355,6 @@
                 "node": ">= 8"
             }
         },
-        "node_modules/liftup/node_modules/is-number": {
-            "version": "7.0.0",
-            "dev": true,
-            "license": "MIT",
-            "engines": {
-                "node": ">=0.12.0"
-            }
-        },
         "node_modules/liftup/node_modules/micromatch": {
             "version": "4.0.5",
             "dev": true,
@@ -3409,17 +3367,6 @@
                 "node": ">=8.6"
             }
         },
-        "node_modules/liftup/node_modules/to-regex-range": {
-            "version": "5.0.1",
-            "dev": true,
-            "license": "MIT",
-            "dependencies": {
-                "is-number": "^7.0.0"
-            },
-            "engines": {
-                "node": ">=8.0"
-            }
-        },
         "node_modules/lines-and-columns": {
             "version": "1.2.4",
             "resolved": "https://registry.npmjs.org/lines-and-columns/-/lines-and-columns-1.2.4.tgz",
@@ -4770,6 +4717,18 @@
             "dev": true,
             "license": "MIT"
         },
+        "node_modules/to-regex-range": {
+            "version": "5.0.1",
+            "resolved": "https://registry.npmjs.org/to-regex-range/-/to-regex-range-5.0.1.tgz",
+            "integrity": "sha512-65P7iz6X5yEr1cwcgvQxbbIw7Uk3gOy5dIdtZ4rDveLqhrdJP+Li/Hx6tyK0NEb+2GCyneCMJiGqrADCSNk8sQ==",
+            "dev": true,
+            "dependencies": {
+                "is-number": "^7.0.0"
+            },
+            "engines": {
+                "node": ">=8.0"
+            }
+        },
         "node_modules/toidentifier": {
             "version": "1.0.1",
             "dev": true,
diff --git a/src/openseadragon.js b/src/openseadragon.js
index 499ab310..33ccf20c 100644
--- a/src/openseadragon.js
+++ b/src/openseadragon.js
@@ -2595,6 +2595,7 @@ function OpenSeadragon( options ){
          * Preexisting formats that are not being updated are left unchanged.
          * By default, the defined formats are
          * <pre><code>{
+         *      avif: true,
          *      bmp:  false,
          *      jpeg: true,
          *      jpg:  true,
@@ -2662,6 +2663,7 @@ function OpenSeadragon( options ){
 
 
     var FILEFORMATS = {
+            avif: true,
             bmp:  false,
             jpeg: true,
             jpg:  true,