From the start Doctrine has been designed to work with multiple connections. Unless separately specified Doctrine always uses the current connection for executing the queries. The following example uses {{openConnection()}} second argument as an optional connection alias. // Doctrine_Manager controls all the connections $manager = Doctrine_Manager::getInstance(); // open first connection $conn = $manager->openConnection(new PDO('dsn','username','password'), 'connection 1'); For convenience {{Doctrine_Manager}} provides static method {{connection()}} which opens new connection when arguments are given to it and returns the current connection when no arguments have been speficied. // open first connection $conn = Doctrine_Manager::connection(new PDO('dsn','username','password'), 'connection 1'); $conn2 = Doctrine_Manager::connection(); // $conn2 == $conn The current connection is the lastly opened connection. // open second connection $conn2 = $manager->openConnection(new PDO('dsn2','username2','password2'), 'connection 2'); $manager->getCurrentConnection(); // $conn2 You can change the current connection by calling {{setCurrentConnection()}}. $manager->setCurrentConnection('connection 1'); $manager->getCurrentConnection(); // $conn You can iterate over the opened connection by simple passing the manager object to foreach clause. This is possible since {{Doctrine_Manager}} implements special {{IteratorAggregate}} interface. // iterating through connections foreach($manager as $conn) { }